Penicillin G Sodium Salt

Penicillin G Sodium Salt

Research-Grade β-Lactam Antibiotic
Catalog Number: AS-2040

Product Information

• Catalog Number: AS-2040

• CAS Number: 69-57-8

• Molecular Formula: C₁₆H₁₇N₂NaO₄S

• Molecular Weight: 356.37 g/mol

• Form: Powder

Overview

Penicillin G Sodium Salt is a β-lactam class antibiotic widely used in microbiological research and laboratory studies. It exerts its antibacterial activity by inhibiting bacterial cell wall synthesis through interaction with penicillin-binding proteins (PBPs), leading to loss of cell wall integrity and bacterial cell lysis under laboratory conditions.

The compound is primarily active against Gram-positive bacteria, including many streptococci and non-penicillinase-producing staphylococci. Due to susceptibility to β-lactamase enzymes, its activity against Gram-negative organisms is limited.

Penicillin G Sodium Salt is commonly employed as a reference antibiotic in studies of cell wall biosynthesis, antimicrobial susceptibility, and bacterial physiology.

Applications

• Research on bacterial cell wall synthesis

• Studies involving penicillin-binding proteins (PBPs)

• Antimicrobial susceptibility and resistance research

• General microbiological and biochemical investigations

Mechanism of Action

Penicillin G inhibits the transpeptidation step of peptidoglycan synthesis by binding to PBPs. This disrupts cell wall assembly, resulting in weakened structural integrity and inhibition of bacterial growth.

Key Features & Benefits

• Classical β-lactam antibiotic with well-defined mechanism of action

• Effective against a broad range of Gram-positive bacteria

• Highly soluble sodium salt suitable for aqueous laboratory preparations

• Suitable for controlled research and reference applications

Solubility & Stability

• Solubility: Freely soluble in water

• Short-term storage (solid): 2–8 °C

• Long-term storage (solid): −20 °C

• Prepared solutions: Stability dependent on concentration and temperature; prepare fresh where possible

Storage & Handling

• Store in a tightly closed container

• Protect from moisture and light

• Handle using appropriate laboratory safety practices

Intended Use

For laboratory research use only.
Not for human or animal use.

Quality & Compliance

• Supplied for research and laboratory applications

• Manufactured and handled under controlled conditions

• SDS and COA available upon request

Customs & Trade Information

HS / AHECC Code: 2941.10.00
Penicillins and derivatives