Albendazole

Albendazole — High-Purity Research Grade

Benzimidazole Compound for Parasitology & Microtubule Studies

Catalog Number: AC-2051
CAS Number: 54965-21-8

Overview

Albendazole is a benzimidazole derivative supplied in high-purity research grade for use in laboratory and academic studies. It is widely employed as a model compound in investigations of antiparasitic mechanisms, microtubule dynamics, and cellular energy metabolism.

In experimental systems, albendazole is known to interact with β-tubulin, disrupting microtubule polymerisation and downstream metabolic processes. Due to this well-characterised mechanism, albendazole is frequently used in parasitology research, veterinary pharmacology studies, and preclinical repurposing research, including oncology and infectious disease models.

Chemical & Physical Properties

• Molecular Formula: C₁₂H₁₅N₃O₂S

• Molecular Weight: 265.33 g/mol

• Appearance: White to off-white crystalline powder

• Purity: ≥ 98.7 %

• Chemical Class: Benzimidazole derivative

Key Features & Benefits

• High-purity material suitable for reproducible research results

• Well-studied β-tubulin interaction model compound

• Widely referenced in parasitology and cell biology literature

• Suitable for mechanistic, pharmacokinetic, and screening studies

Typical Research Applications

Parasitology & Veterinary Research

• Investigation of antiparasitic mechanisms

• Studies of nematode and cestode energy metabolism

• Veterinary pharmacology and formulation research

Cell Biology & Biochemistry

• Microtubule polymerisation and cytoskeleton studies

• Glucose uptake and metabolic inhibition models

Preclinical & Translational Research

• Oncology research models exploring microtubule disruption

• Infectious disease and drug-repurposing screening studies

Mechanism of Action (Research Context)

In experimental systems, albendazole binds selectively to β-tubulin, preventing normal microtubule assembly. This disruption interferes with intracellular transport and energy metabolism, making albendazole a valuable tool compound for studying microtubule-dependent biological processes.

Storage & Handling

• Store tightly sealed

• Temperature: 2–8 °C

• Protect from moisture and direct light

• Handle using appropriate laboratory PPE

Intended Use

For laboratory and research use only.
Not for human or veterinary therapeutic use.
Not for food, feed, or diagnostic applications.

Quality & Documentation

• Supplied with Certificate of Analysis (COA)

• Safety Data Sheet (SDS) available upon request

• Manufactured and handled under controlled quality conditions

Customs & Trade Information

HS / AHECC Code: 2933.99
Heterocyclic compounds with nitrogen hetero-atom(s), not elsewhere specified