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Ausamics FendaPure™ — Fenbendazole ≥99.7% (EP Grade)
$19.50 AUD
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AuSaMicS Life Science™ · Benzimidazole Compounds · Research Grade Reagents
Fenbendazole ≥99.7% EP Grade — FendaPure™
Methyl 5-(phenylthio)-2-benzimidazolecarbamate | CAS: 43210-67-9 | Cat: ASA-2046
High-purity fenbendazole manufactured to European Pharmacopoeia standards, verified at ≥99.7% by HPLC. Australian stock held in Thomastown, VIC — available to verified research institutions, NATA-accredited laboratories, and universities across Australia.
≥99.7% EP Grade ✓ AU Stock Melbourne 📋 COA + SDS Included 🏛 Institutions Only 🔬 Research Use Only
Quick Specs
CAS Number43210-67-9
CatalogueASA-2046
MW299.35 g/mol
FormulaC₁₅H₁₃N₃O₂S
Purity≥99.7% (HPLC)
GradeEuropean Pharmacopoeia
HS Code2933.99
Overview
FendaPure™ Fenbendazole (ASA-2046) is a benzimidazole carbamate compound widely used in parasitological research, pharmacology, and molecular cell biology. Manufactured to European Pharmacopoeia (EP) grade standards and verified at ≥99.7% purity by HPLC, FendaPure™ delivers consistent, reproducible results across a wide range of in vitro research applications.
Supplied as a fine white to off-white crystalline powder, stable at ambient conditions and soluble in DMSO and organic solvents. Complete analytical documentation — COA, SDS, and TDS — is included with every order.
Research Applications
Parasitology & Helminthology
Reference standard for in vitro studies on nematode and cestode biology, tubulin polymerisation inhibition, and anthelmintic mechanism characterisation.
Cell Biology & Cytoskeletal Research
Investigation of microtubule dynamics, mitotic spindle disruption, and tubulin-binding pharmacology in mammalian and helminth cell systems.
Pharmacology & Drug Metabolism
ADMET profiling, metabolite identification, and comparative bioavailability studies in preclinical pharmacological research models.
Pharmaceutical QC & Reference
High-purity EP-grade material suitable as analytical reference standard for method development, validation, and regulatory compliance testing.
Academic & Institutional Research
Widely cited in peer-reviewed literature as a model benzimidazole for studies in veterinary pharmacology, anti-parasitic resistance, and comparative biochemistry.
Microbiome Interaction Studies
Evaluation of benzimidazole effects on gut microbiome composition and host–parasite–microbiota interaction models.
Why Choose FendaPure™ ASA-2046?
| Purity Guarantee | ≥99.7% by HPLC — EP Grade standard, batch-verified |
| Supply Chain | Australian-held stock in Melbourne — no 4–6 week import wait |
| Documentation | Full COA, SDS (GHS/WHS compliant), and TDS supplied with every order |
| Batch Consistency | Each lot independently tested; results available on request |
| Technical Support | Direct support from the product formulator — not a call centre |
| Eligibility | 🏛 Verified research institutions, NATA labs, and universities only. Quote request required. |
Cross-Reference / Equivalent Products
FendaPure™ ASA-2046 is comparable to the following commercial reference materials.
| Supplier | Product / Cat. No. | Purity | AU Stock | Institutional Supply |
|---|---|---|---|---|
| AuSaMicS Life Science ← You are here | FendaPure™ ASA-2046 | ≥99.7% EP | ✔ Melbourne | ✔ Verified buyers |
| Sigma-Aldrich (Merck) | Fenbendazole F5396 | ≥99% (HPLC) | Import | – |
| Cayman Chemical | Fenbendazole 14427 | ≥98% | Import | – |
| TCI Chemicals | Fenbendazole F0346 | ≥98.0% | Import | – |
| Alfa Aesar (Thermo) | Fenbendazole J64721 | 98% | Import | – |
Request a Quote
This product is available to verified institutional buyers. Submit a quote request and our team will confirm eligibility and provide full pricing within one business day.
💬 Request a Quote →Chemical Identity
| IUPAC Name | Methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate |
| Common Names | Fenbendazole; Fenbendasole; SKF-62979; Panacur® (veterinary brand) |
| CAS Number | 43210-67-9 |
| Molecular Formula | C₁₅H₁₃N₃O₂S |
| Molecular Weight | 299.35 g/mol |
| InChI Key | NZXKDOXZBBGIDQ-UHFFFAOYSA-N |
| HS Code | 2933.99 |
Physical & Chemical Properties
| Appearance | White to off-white crystalline powder |
| Purity | ≥99.7% (HPLC) — European Pharmacopoeia Grade |
| Melting Point | 233–237 °C |
| Solubility (DMSO) | ≥30 mg/mL |
| Solubility (Acetone) | Soluble |
| Solubility (Water) | <0.1 mg/mL (practically insoluble) |
| Log P (calc.) | 3.12 |
| pKa (calc.) | ~4.2 (benzimidazole N-H) |
Quality & Analytical Data
| Identity Method | IR Spectroscopy, HPLC retention time, NMR (on request) |
| Purity Method | Reverse-phase HPLC (C18 column) |
| Residual Solvents | Below ICH Q3C Class 3 limits |
| Heavy Metals | Tested; compliant with EP limits |
| Water Content (KF) | ≤0.5% |
Storage & Stability
Storage: Store at 15–25 °C, dry, protected from light. Sealed amber glass or HDPE container. Stable for ≥24 months from manufacture date under recommended conditions.
| Storage Temperature | 15–25 °C (ambient, controlled) |
| Light Sensitivity | Moderate — store away from UV |
| Shelf Life | ≥24 months under recommended conditions |
| GHS Signal Word | Warning |
| GHS Hazard Codes | H302 (Harmful if swallowed); H361 (Suspected reproductive toxicant) |
| PPE Required | Lab coat, nitrile gloves, safety glasses; work in ventilated area |
Mode of Action
Fenbendazole exerts its primary pharmacological action through selective binding to β-tubulin, the structural subunit of microtubules. This binding inhibits tubulin polymerisation, disrupting the cytoskeletal network and mitotic spindle apparatus. In helminth models, this impairs glucose uptake, energy metabolism, and cell division.
Fenbendazole binds β-tubulin (colchicine-binding site)
↓
Inhibition of tubulin polymerisation
↓
Disruption of mitotic spindle & cytoskeletal integrity
↓
Impaired glucose transport & energy depletion
↓
Cell cycle arrest / cell death (parasite or target cell)
↓
Inhibition of tubulin polymerisation
↓
Disruption of mitotic spindle & cytoskeletal integrity
↓
Impaired glucose transport & energy depletion
↓
Cell cycle arrest / cell death (parasite or target cell)
Fenbendazole binds with higher selectivity to parasite tubulin than to mammalian tubulin isoforms — making it a valuable tool for species-specific tubulin pharmacology research. At research concentrations it is routinely used as a positive control for microtubule disruption assays.
Technical Overview
| Pharmacological Class | Benzimidazole carbamate; β-tubulin polymerisation inhibitor |
| Primary Target | β-tubulin (colchicine-binding site) |
| IC₅₀ (tubulin polymerisation) | ~1–10 µM (cell-line and species dependent) |
| Selectivity | Parasite > mammalian tubulin (structure-dependent) |
| Metabolites of Interest | Fenbendazole sulfoxide (oxfendazole); fenbendazole sulfone |
| Typical Working Conc. | 0.1–50 µM depending on assay system |
| Vehicle Recommendation | Dissolve in DMSO to 10–30 mM stock; dilute in buffer/media (<0.1% DMSO final) |
Selected Literature References
- Lacey, E. (1988). The role of tubulin in the mode of action and mechanism of drug resistance to benzimidazoles. International Journal for Parasitology, 18(7), 885–936.
- Borgers, M. et al. (1975). Influence of mebendazole on microtubules in nematode intestinal cells. American Journal of Veterinary Research, 36(8), 1153–1166.
- Friedman, P.A. & Platzer, E.G. (1978). Interaction of benzimidazoles with bovine brain tubulin. Biochimica et Biophysica Acta, 544(3), 605–614.
- Mottier, L. et al. (2006). Drug transport in helminth parasites: passive diffusion of benzimidazoles. Experimental Parasitology, 113(1), 49–57.
- Dogra, N. et al. (2018). Fenbendazole as a moderate microtubule destabilizing agent. Scientific Reports, 8, 11926.
Available Pack Sizes
| Pack Size | Recommended For | Typical Use Case |
|---|---|---|
| 5 g | Trial / Method Development | Protocol optimisation, initial feasibility testing |
| 10 g | Small-Scale Research | Short-term in vitro studies, student projects |
| 25 g | Standard Laboratory Use | Ongoing research programmes, mid-scale assays |
| 50 g | Extended Studies | Multi-assay research, in vivo model experiments |
| 100 g | Active Research Groups | Continuous supply; lowest cost-per-gram |
| 200 g | Bulk / Institutional Supply | Core facilities, multi-project departments |
How to order: Submit a quote request via the link below. Our team will confirm your institutional eligibility and provide pricing and dispatch timeline within one business day. Custom quantities above 200 g available on request.
Order Information
| Catalogue Number | ASA-2046 |
| Ordering Process | Quote request required — institutional verification before dispatch |
| Dispatch | Confirmed orders dispatched within 1–2 business days from Melbourne |
| Shipping | Australia-wide via registered courier; cold-pack not required |
| Minimum Order | 5 g |
| Payment | EFT, purchase order (institutional accounts); credit card on approval |
| Documentation | COA, SDS, TDS provided with every shipment |
Ready to Order?
Submit your institution details and pack size requirements. We’ll confirm eligibility and provide a formal quote within one business day.
💬 Request a Quote →Available Documents
Every order of FendaPure™ ASA-2046 includes a full analytical and safety documentation package. Documents may also be requested prior to purchase by emailing us.
| Certificate of Analysis (COA) | Batch-specific HPLC purity, identity confirmation, lot number, expiry. Request COA → |
| Safety Data Sheet (SDS) | Full 16-section GHS/WHS 2023 compliant SDS (Australian format). Request SDS → |
| Technical Data Sheet (TDS) | Physicochemical data, solubility guide, storage conditions, handling recommendations. |
| Product Datasheet (PD) | Summary product information for institutional procurement and record-keeping. |
Regulatory & Compliance Notes
| Standard Applied | European Pharmacopoeia (EP) monograph requirements |
| GHS Classification (AU) | WHS Regulations 2017 (Cth); GHS 7th Edition |
| SUSMP Schedule | ⚠️ Schedule 4 (Prescription Only) for non-veterinary use — per TGA Poisons Standard October 2025. Supply restricted to verified institutional research buyers. Confirm current scheduling at tga.gov.au before ordering. |
| TGA Status | Supplied for analytical research use only — not registered as a therapeutic good |
| Buyer Requirement | Institutional purchase order or verified research affiliation required prior to dispatch |
Pre-purchase documentation: Email support@ausamics.com.au with your catalogue number. All documents dispatched within one business day. Institutional procurement teams can receive full documentation prior to order placement.
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