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Cycloheximide research-grade powder used to inhibit fungal growth in laboratory studies
  • Cycloheximide research-grade powder used to inhibit fungal growth in laboratory studies
  • Cycloheximide research-grade powder used to inhibit fungal growth in laboratory studies
Cycloheximide

Cycloheximide

$29.00
Weight

Cycloheximide

Eukaryotic Protein Synthesis Inhibitor (Research Grade)
Catalog Number: AS-2038

Product Information

  • Catalog Number: AS-2038

  • CAS Number: 66-81-9

  • Molecular Formula: C₁₅H₂₃NO₄

  • Molecular Weight: 281.35 g/mol

  • Form: Powder

Overview

Cycloheximide is a potent inhibitor of eukaryotic protein synthesis, widely used in microbiological, cell biology, and molecular biology research. It acts by binding to the 60S ribosomal subunit of eukaryotic cells, thereby blocking translational elongation and effectively inhibiting protein synthesis.

Due to this mechanism, cycloheximide is commonly used to suppress fungal and yeast growth in microbiological culture media. Most bacteria are naturally resistant to cycloheximide, making it useful for selectively inhibiting eukaryotic organisms without significantly affecting bacterial populations.

Applications

  • Suppression of fungal and yeast growth in microbiological media

  • Studies of eukaryotic protein synthesis and translation

  • Cell biology research involving protein turnover and stability

  • Experimental investigation of ribosomal function in eukaryotes

Mechanism of Action

Cycloheximide binds to the 60S ribosomal subunit in eukaryotic cells, inhibiting peptide chain elongation during translation. This results in rapid and effective inhibition of protein synthesis in fungi and other eukaryotic organisms.

Key Features & Benefits

  • Strong and selective inhibitor of eukaryotic protein synthesis

  • Commonly used to inhibit fungal and yeast growth

  • Limited activity against bacteria due to natural resistance

  • Well-characterised mechanism and reproducible performance

Storage & Stability

  • Store in a cool, dry place

  • Protect from moisture and light

  • Keep container tightly closed when not in use

Intended Use

For laboratory research use only.
Not for human or animal use.

Quality & Compliance

  • Supplied for research and laboratory applications

  • Manufactured and handled under controlled conditions

  • SDS and COA available upon request

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