Amikacin Sulfate Powder

Amikacin Sulfate Powder

High-Purity Aminoglycoside Antibiotic for Research & Microbiological Applications

Catalog Number: AS-2045
CAS Number: 39831-55-5

Overview

Amikacin Sulfate is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A, supplied in high-purity research grade for laboratory and industrial applications. It exhibits broad-spectrum activity against many Gram-negative bacteria and selected Gram-positive organisms, and is widely used as a reference compound in microbiological, pharmaceutical, and cell culture research.

Ausamics Amikacin Sulfate Powder is manufactured under controlled quality conditions to ensure consistent potency, solubility, and reproducibility, making it suitable for microbial inhibition studies, selective media, and in-vitro research workflows.

Key Features & Benefits

• Broad-spectrum aminoglycoside antibiotic

• High-purity powder with consistent batch performance

• Freely soluble in water for easy preparation

• Suitable for microbiological assays and cell culture research

• Quality aligned with USP reference specifications

Chemical & Physical Properties

• Chemical Name: Amikacin Sulfate

• Molecular Formula: C₂₂H₄₃N₅O₁₃ · 2H₂SO₄

• Molecular Weight: 781.75 g/mol

• Appearance: White to off-white crystalline powder

• Solubility: Freely soluble in water; practically insoluble in alcohol and acetone

• Chemical Class: Aminoglycoside antibiotic

Typical Research Applications

Microbiology & Antimicrobial Research

• Selective agent in culture media

• Suppression of contaminant bacterial growth

• Antimicrobial susceptibility testing

• Studies of aminoglycoside resistance mechanisms

Cell Culture & Molecular Biology

• Control of bacterial contamination in cell culture systems

• Use as a selection agent in engineered cell lines expressing aminoglycoside-modifying enzymes

• In-vitro assay development

Pharmaceutical & Process Research

• Reference material in formulation and stability studies

• API research and analytical method development

Mechanism of Action (Research Context)

In experimental systems, amikacin binds to the 30S ribosomal subunit, disrupting bacterial protein synthesis and leading to inhibition of cell growth. This well-characterised mechanism makes it a valuable tool compound for studies of translation, resistance pathways, and antimicrobial screening.

Storage & Handling

• Store tightly sealed

• Protect from moisture and light

• Recommended storage temperature: 2–8 °C

• Handle using appropriate laboratory PPE

Intended Use

For laboratory and research use only.
Not for human or veterinary therapeutic use.
Not for food, feed, or diagnostic applications.

Quality & Documentation

• Supplied with Certificate of Analysis (COA)

• Safety Data Sheet (SDS) available upon request

• Manufactured under controlled quality systems for batch consistency

Customs & Trade Information

HS / AHECC Code: 2941.90
Antibiotics, other