Cefoperazone Powder

Cefoperazone Powder
Broad-Spectrum Cephalosporin Antibiotic for Microbiological Applications

Catalog Number: AS-2005
CAS Number: 62893-19-0
Molecular Weight: 645.67 g/mol
Molecular Formula: C₂₅H₂₇N₉O₈S₂

Overview
Cefoperazone Powder is a third-generation cephalosporin antibiotic widely used in microbiology for selective media preparation and antimicrobial research applications. It exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria, including clinically significant organisms such as Pseudomonas aeruginosa.

Due to its stability and activity profile, cefoperazone is commonly incorporated into selective culture media formulations to suppress competing flora while permitting the growth of target organisms.

Mechanism of Action
Cefoperazone is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis. It binds to specific penicillin-binding proteins (PBPs), which are essential enzymes involved in peptidoglycan cross-linking during cell wall formation. By inhibiting PBPs, cefoperazone disrupts the final stages of cell wall assembly, leading to structural instability and eventual bacterial cell lysis through autolysin-mediated degradation.

Applications
• Preparation of selective microbiological media
• Antimicrobial susceptibility and resistance research
• Suppression of Gram-negative contaminants in culture systems
• Laboratory research involving beta-lactam antibiotic mechanisms

Key Features & Benefits
• Broad-spectrum activity against Gram-positive and Gram-negative bacteria
• Effective against Pseudomonas aeruginosa
• Stable beta-lactam antibiotic suitable for laboratory formulations
• High purity powder suitable for research and media supplementation

Handling & Preparation
Prepare stock solutions using sterile water or appropriate solvent under aseptic conditions.
Filter sterilise when required before adding to cooled media.
Avoid repeated freeze–thaw cycles to maintain potency.

Storage & Stability
Store tightly sealed in a cool, dry place as recommended on the label.
Protect from moisture and light.
Prepared solutions should be stored refrigerated and used within recommended timeframes.

Intended Use
For laboratory research use only.
Not for human, veterinary, pharmaceutical, or therapeutic use.

Quality & Compliance
Manufactured under controlled conditions to ensure consistent purity and performance.
Suitable for microbiology research and selective media formulation applications.