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Ciprofloxacin Hydrochloride | Fluoroquinolone Antibiotic Research Reagent
$27.00 AUD
Documentation
AuSaMicS Ciprofloxacin Hydrochloride (CAT: ASA-2048) is a high-purity (≥ 99%) broad-spectrum antibiotic of the fluoroquinolone class, supplied exclusively for research use. It acts by inhibiting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, making it a well-characterised tool for antimicrobial resistance research, pharmacokinetic studies, and microbiological assays. Active against a wide range of gram-negative and gram-positive bacteria.
Product specifications
| Catalog number | ASA-2048 |
| CAS number | 86393-32-0 |
| Chemical formula | C₁₆H₁₅FN₃O₃·HCl |
| Molecular weight | 367.81 g/mol |
| Class | Fluoroquinolone (2nd generation) |
| Grade | Research Use Only |
| Appearance | White to slightly yellow crystalline powder |
| Purity | ≥ 99% (HPLC) |
| Solubility | Soluble in water and dilute acid; slightly soluble in ethanol |
| Mechanism of action | Inhibition of DNA gyrase (topoisomerase II) and topoisomerase IV |
| Spectrum | Broad-spectrum — gram-negative and gram-positive bacteria |
Key features
Broad-spectrum activity — effective against a wide range of gram-negative and gram-positive bacteria
High purity ≥ 99% (HPLC) — ensures reliable and reproducible research results
Well-characterised mechanism — dual inhibition of DNA gyrase and topoisomerase IV
Versatile research tool — suitable for in vitro MIC testing, in vivo infection models, and resistance studies
Consistent batch quality — thoroughly tested and released with full COA
Research applications
Bacterial resistance mechanisms — QRDR mutations, efflux pumps, plasmid-mediated resistance
Pharmacokinetic and pharmacodynamic studies — AUC/MIC modelling
MIC determination, time-kill kinetics, and biofilm inhibition assays
Disk diffusion, broth microdilution, and susceptibility testing
DNA gyrase inhibition and SOS pathway induction studies
In vitro and in vivo infection models
Stock solution preparation
1
Dissolve in sterile water or 0.1 N HCl to prepare a concentrated stock solution (e.g. 10 mg/mL).
2
Filter-sterilise through a 0.22 μm membrane filter before use in cell culture or microbiological assays.
3
Dilute to working concentration in appropriate buffer or medium immediately before use.
4
Store prepared stock solutions at −20°C in aliquots. Avoid repeated freeze-thaw cycles.
Storage
Solid powder: Refrigerator (2–8°C) — away from moisture, heat, and direct light
Stock solutions: −20°C in aliquots — avoid repeated freeze-thaw cycles
Refer to product label for shelf life
Safety information
WARNING — GHS Hazard Classification: H302 Harmful if swallowed · H318 Causes serious eye damage · H361 Suspected reproductive toxin · H373 May cause organ damage (repeated exposure).
Wear nitrile gloves, safety goggles, and laboratory coat. Avoid breathing dust. Women of childbearing potential should apply additional precautions (suspected reproductive toxin). In case of eye contact, rinse immediately with water for at least 15 minutes and seek immediate medical attention. Full SDS available upon request.
Wear nitrile gloves, safety goggles, and laboratory coat. Avoid breathing dust. Women of childbearing potential should apply additional precautions (suspected reproductive toxin). In case of eye contact, rinse immediately with water for at least 15 minutes and seek immediate medical attention. Full SDS available upon request.
Environmental note
Ciprofloxacin is an active broad-spectrum antibiotic. Do not discharge to drains, waterways, or soil. Discharge may drive antimicrobial resistance in environmental microbiota. Treat all waste as pharmaceutical/bioactive chemical waste and dispose via a licensed waste contractor.
Intended use
For Research Use Only. Not for human or veterinary therapeutic use, food, feed, or pharmaceutical manufacturing. Classified as Schedule 4 (Prescription Only) in Australia when used therapeutically — this product is supplied exclusively for laboratory research by qualified professionals.
Quality & documentation
Manufactured and tested to research grade standards. Full batch-specific Certificate of Analysis (COA), Technical Data Sheet (TDS), and Safety Data Sheet (SDS) available upon request. For bulk quantities or contract pricing, contact support@ausamics.com or visit ausamics.com.au.
✓ ≥ 99% purity (HPLC)
✓ Research use only
✓ COA available
✓ Ships from Australia