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Demi-Fraser Broth Base (Half Fraser Broth) Ausamics

Demi-Fraser Broth Base (Half Fraser Broth) for Listeria Enrichment | AS-1194

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Demi-Fraser Broth Base (Half Fraser Broth) for Listeria Enrichment | AS-1194

Meta Title: Half Fraser Broth for Listeria | AS-1194 | AuSaMicS

Meta Description: Demi-Fraser Broth Base for primary enrichment of Listeria from food and environmental samples. Ideal for ISO 11290 workflows and Listeria recovery.

AuSaMicS Life Science • Listeria Enrichment Media

Demi-Fraser Broth Base (Half Fraser Broth)

Primary Selective Enrichment Medium for Listeria spp.

Selective enrichment broth for the primary recovery of Listeria species, especially Listeria monocytogenes, from food and environmental samples. Half Fraser Broth is designed to recover stressed or injured cells while maintaining sufficient selectivity against background flora, making it the standard first-step enrichment medium in Listeria testing workflows.

AS-1194 🧪 Primary Enrichment Broth ✓ ISO Listeria Workflow 🔬 Esculin Blackening
Use: Primary Listeria enrichment Readout: Brown to black darkening Follow-up: Oxford / ALOA / PALCAM plating

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Best Product Title:
Demi-Fraser Broth Base (Half Fraser Broth) for Listeria Enrichment | AS-1194
Meta Title:
Half Fraser Broth for Listeria | AS-1194 | AuSaMicS
Meta Description:
Demi-Fraser Broth Base for primary enrichment of Listeria from food and environmental samples. Ideal for ISO 11290 workflows and Listeria recovery.
Suggested Pack Sizes
100 g • 500 g • 1 kg • 5 kg

🧪 Complete Formulation & Selective Principle

📋 Typical Composition (per Liter)

Ingredient Concentration Primary Function Contribution
Enzymatic Digest of Casein 5.0 g Nutrient source Supports recovery of stressed Listeria cells
Enzymatic Digest of Animal Tissue 5.0 g Nutrient source Provides peptides and amino acids
Beef Extract 5.0 g Growth support Adds vitamins and trace nutrients
Yeast Extract 5.0 g Growth support Improves viability and resuscitation
Sodium Chloride 20.0 g Selective osmotic pressure Helps inhibit some competing flora
Disodium Phosphate 9.6–12.0 g Buffer system Maintains stable enrichment conditions
Monopotassium Phosphate 1.35 g Buffer system Balances pH during growth
Esculin 1.0 g Differential substrate Hydrolysis contributes to blackening reaction
Lithium Chloride 3.0 g Selective agent Suppresses many competing organisms
Nalidixic Acid 0.01 g Selective agent Reduces Gram-negative background
Acriflavine Hydrochloride 0.012–0.0125 g Selective agent Suppresses many Gram-positive competitors
Ferric Ammonium Citrate 0.5 g Indicator supplement Reacts with esculetin to darken positive broth
Final pH: 7.2 ± 0.2 at 25°C

⚗️ Functional Design

Reduced-Inhibitor Primary Enrichment
Designed to recover stressed or injured Listeria cells before stronger secondary selection
Esculin Blackening System
Positive enrichment darkens as Listeria hydrolyzes esculin
Workflow-Compatible Base
Ideal first step before Fraser Broth, Oxford Agar, or ALOA plating
Why Demi-Fraser Broth? It is the key primary enrichment step when maximum Listeria recovery is needed from difficult food and environmental matrices, especially where cells may be sublethally damaged.

Complete Listeria Workflow Portfolio

Medium Type Workflow Step Best Application Readout Key Advantage
Demi-Fraser Broth Base Selective enrichment broth Primary enrichment Recovery of stressed Listeria from food and environment Blackening of broth Gentler first-step selectivity
Fraser Broth Selective enrichment broth Secondary enrichment Higher selectivity after Half Fraser Blackening of broth Stronger suppression of background flora
Oxford Agar Selective differential agar Plating / isolation Traditional Listeria colony recovery Grey-green colonies with black halo Classic reference plating medium
ALOA Agar Chromogenic agar Plating / differentiation Improved visual species screening Chromogenic colony differentiation Easier visual interpretation
PALCAM Listeria Broth / Agar Selective enrichment / plating Alternative selective workflow High-background sample matrices Esculin-based darkening / halo system Strong selective pressure

Strategic Medium Selection for Listeria Recovery

✅ Demi-Fraser Advantages

  • Better Recovery of Injured Cells: Reduced inhibitor level supports stressed Listeria
  • Standard First Step: Fits mainstream ISO-style Listeria workflows
  • Visible Presumptive Signal: Esculin blackening helps rapid screening
  • Broad Sample Suitability: Food, swabs, dairy, meats, vegetables, surfaces
  • Excellent Sales Positioning: Essential medium in every serious Listeria workflow

⚠️ Method Considerations

  • Not a Final Confirmation Medium: Positive broths must be subcultured and confirmed
  • Supplement Handling Matters: Ferric ammonium citrate and selective supplements must be added correctly
  • Short Ready-to-Use Stability: Supplemented broth is best used fresh
  • Some Competing Esculin-Positive Flora Exist: Follow-up plating remains essential

🎯 Best-Fit Applications

  • Food Safety Labs: Routine Listeria detection in foods and ingredients
  • Environmental Monitoring: Swabs, drains, and food plant surfaces
  • Dairy and RTE Programs: Samples with stressed or low-level contamination
  • Regulatory and Research Labs: ISO-oriented Listeria workflows

📊 Typical Interpretation

Observation Interpretation Next Step Notes
Golden broth turns brown to black Presumptive positive enrichment Subculture to Oxford, ALOA, or PALCAM Typical of esculin-hydrolyzing Listeria growth
Turbid without strong darkening Possible mixed or weak enrichment Proceed to selective plating if required Interpret with sample context
No blackening, clear broth No presumptive reaction Continue per lab workflow May indicate no target recovery or very low counts

💰 Recommended Pack Sizes & Market-Beating Pricing

Pack Size Recommended Price (AUD) Role Strategy
100 g $35–$45 Trial / small lab Entry pack for method validation
500 g $129–$149 Best seller Aggressive value to beat Merck/Oxoid-style pricing
1 kg $229–$259 Routine food labs Best-value pack for repeat QC use
5 kg $980–$1,120 Institutional / distributor Contract and tender-friendly pricing
Recommended pricing position: sell this as an essential ISO-style workflow medium, priced below major multinational brands but clearly above low-end commodity suppliers on technical credibility and documentation.

📋 Technical Specifications

Catalogue Number AS-1194
Medium Type Primary selective enrichment broth
Target Organisms Listeria monocytogenes and other Listeria spp.
Reconstitution Approx. 55–57.9 g/L depending on formulation
Final pH 7.2 ± 0.2 at 25°C
Indicator System Esculin + ferric ammonium citrate
Selective Agents Lithium chloride, nalidixic acid, acriflavine
Incubation 30°C for 24 h typical primary enrichment
Supplement Addition Ferric ammonium citrate after sterilization
Prepared Broth Use Best used fresh after supplementation

🧫 Primary Applications

  • ✓ Primary enrichment of food and environmental samples for Listeria testing
  • ✓ Recovery of stressed or low-level Listeria contamination
  • ✓ First-step enrichment before Fraser Broth and selective plating
  • ✓ Food safety, dairy, meat, ready-to-eat, and environmental monitoring workflows

⚗️ Preparation Protocol

  1. 1. Suspend the dehydrated base in purified water.
  2. 2. Heat with agitation until completely dissolved.
  3. 3. Sterilize at 121°C for 15 minutes.
  4. 4. Cool and aseptically add ferric ammonium citrate supplement.
  5. 5. Inoculate sample homogenate and incubate for primary enrichment before subculture.

📦 Storage & Intended Use

Dehydrated medium: Store tightly closed in a cool, dry place.

Prepared supplemented broth: Best used fresh; refrigerated short-term only if necessary.

Workflow note: Positive enrichments should be subcultured and confirmed by selective agar and standard laboratory identification methods.

Notice: For food and environmental microbiology use only.

AuSaMicS Life Science: Professional microbiology media for food safety, environmental monitoring, quality control, research, and standardized pathogen detection workflows. Product information is provided for laboratory and technical evaluation purposes only.

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