Oxytetracycline Dihydrate is a broad-spectrum tetracycline-class antibiotic widely used in microbiological research, laboratory studies, and culture media applications. It acts by inhibiting bacterial protein synthesis through binding to the 30S ribosomal subunit, making it effective against a wide range of Gram-positive and Gram-negative bacteria.

In laboratory settings, oxytetracycline is commonly used as a selective agent to suppress susceptible microorganisms, or to study antibiotic-resistance mechanisms, microbial physiology, and genetic selection systems. AuSaMicS Oxytetracycline Dihydrate is supplied as BP 2022, injectable-grade bulk material for research and laboratory use — offering consistent quality, defined potency, reproducible performance, and full batch traceability with certificate of analysis.

Oxytetracycline reversibly binds the 30S ribosomal subunit of susceptible bacteria, blocking attachment of aminoacyl-tRNA to the mRNA–ribosome complex and arresting protein synthesis. This bacteriostatic mechanism underlies its use both as a selective supplement in culture media (typically 10–50 µg/mL) and as a research tool for studying ribosomal function, translation, and antibiotic-resistance gene expression (e.g. tet efflux-pump and ribosomal-protection systems).

• Broad-spectrum activity against Gram-positive and Gram-negative bacteria
• Inhibits bacterial protein synthesis (30S ribosomal subunit)
• Widely used as a selective agent in microbiological media
• Suitable for antibiotic resistance and genetic studies
• Each batch supplied with a full Certificate of Analysis and defined re-test date

Microbiology & Research:

• Selective agent in bacterial and fungal culture media
• Suppression of susceptible bacteria during mixed-culture studies
• Antibiotic resistance research
• Genetic selection and plasmid maintenance studies

Biotechnology & Academic Research:

• Studies of protein synthesis inhibition
• Microbial physiology and growth-response analysis
• Method development and validation

Cross-reference numbers are provided as a general equivalence guide only; always confirm current catalogue codes and specifications directly with the respective supplier before substitution.

• "Where to buy oxytetracycline dihydrate BP grade Australia"
• "Oxytetracycline selective agent for bacterial culture media"
• "Injectable grade oxytetracycline dihydrate CAS 6153-64-6 supplier"
• "Tetracycline antibiotic for plasmid selection research"
• "BP 2022 compliant oxytetracycline with certificate of analysis"

Oxytetracycline reversibly binds the 30S ribosomal subunit, blocking aminoacyl-tRNA attachment and arresting bacterial protein synthesis — producing a bacteriostatic effect across a broad range of Gram-positive and Gram-negative organisms.

• Prepare stock solutions in sterile distilled water or dilute acid; filter-sterilise (0.22 µm) — do not autoclave
• Protect from light; add to culture media only after autoclaving and cooling to ≤50 °C
• Store dry powder and stock solutions at 2–8 °C, protected from light

• British Pharmacopoeia Commission (2022). British Pharmacopoeia 2022 — Monograph: Oxytetracycline Dihydrate.
• Chopra, I. & Roberts, M. (2001). Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiology and Molecular Biology Reviews, 65(2), 232–260.
• Griffin, M.O. et al. (2010). Tetracyclines: a pleiotropic family of compounds. American Journal of Physiology-Cell Physiology, 299(3), C539–C548.

• Handle in a fume hood or with local exhaust ventilation; avoid generating dust
• Wear nitrile gloves, safety glasses/goggles, and a laboratory coat
• Store at 2–8 °C, protected from light, tightly closed
• Wash hands thoroughly after handling; do not eat, drink or smoke while handling

Very toxic to aquatic life with long-lasting effects (H400/H410). Avoid release to drains, waterways or soil.

This is a summary only. Refer to the full 16-section Safety Data Sheet (GHS7 / Safe Work Australia WHS format) for complete hazard, toxicological, ecological, transport and regulatory information before use.

Every AuSaMicS Oxytetracycline Dihydrate pack ships with a batch-specific Certificate of Analysis. Current released batches:

Full batch-specific Certificates of Analysis (including related-substance breakdown and identification tests A–D) are available for download below or on request, quoting the lot number printed on your product label.